Dexpanthenol / panthenol is an alcohol analogue of pantothenic acid, which, as a result of intermediate transformations, has the same biological activity as pantothenic acid, but it is better absorbed when applied topically. Pantothenic acid is a water-soluble vitamin that participates in various metabolic processes in the form of coenzyme A. Pantothenic acid is necessary for the formation and regeneration of skin and mucous membranes. With local application, dexpanthenol / panthenol is able to compensate for the increased need of damaged skin or mucous membranes for pantothenic acid.
In pharmacokinetic studies of panthenol labeled with radioactive tritium, it was proved that the substance is characterized by reabsorption through the skin.
Indication
Non-infectious keratopathies, including corneal dystrophies, corneal degenerations, recurrent corneal erosions and prevention of corneal damage when wearing contact lenses.
Comprehensive treatment of corneal and conjunctival damage, chemical and thermal burns.
In the complex therapy of infectious lesions of the cornea of bacterial, viral and fungal origin.
Contraindication
Increased sensitivity to the components of the drug.
Method of application and dosage
The drug is intended for local use.
Depending on the severity and severity of the symptoms, prescribe 1 drop in the conjunctival sac of the affected eye 4 times a day and before going to bed.
The drug should be used until the desired therapeutic effect is obtained.
The duration of treatment depends on the clinical picture and is set individually.
To prevent contamination of the drug and the tip during administration, do not touch the eyelids, the area around the eyes, or other surfaces.
Children.
The safety of the drug in children has not been studied.
Overdose
It is unknown.
Features of application
Corneregel should not be used for the treatment of infectious lesions of the cornea of bacterial, viral and fungal origin as monotherapy, the drug should be used only as an adjunct in the complex therapy of these diseases.
Corneregel contains the preservative cetrimide, which, especially with frequent or long-term use, can cause eye irritation (redness, burning sensation and foreign body in the eye) and can damage the corneal epithelium. For the long-term treatment of chronic dry keratoconjunctivitis, preference should be given to medical preparations that do not contain preservatives.
Corneregel should not be buried with inserted contact lenses, as the material of the lenses may be incompatible with the drug; they should be removed from the eye and inserted again no earlier than 10-15 minutes after instillation of Corneregel.
Use during pregnancy or breastfeeding.
Controlled studies of the use of the drug during pregnancy and breastfeeding have not been conducted. In animal studies, no direct or indirect harmful effects of the drug on pregnancy, embryo / fetal development, childbirth and postnatal development were found. The drug penetrates into breast milk. Therefore, if it is necessary to use the drug during pregnancy and breastfeeding, the doctor must carefully weigh the ratio of the expected benefit from Corneregel treatment for the mother and the potential risk for the fetus / child.
The ability to influence the speed of reaction when driving vehicles or other mechanisms.
Within a few minutes after instillation of Corneregel in the conjunctival sac, a temporary deterioration of vision is possible. It is not recommended to drive vehicles or work with complex mechanisms until visual acuity is restored.
Composition
active substance: dexpanthenol;
1 g of eye gel contains dexpanthenol 50 mg
Excipients: cetrimide, trilon B, carbomer, sodium hydroxide, water for injections.
Storage conditions
Store at a temperature not higher than 25 °C in a place inaccessible to children.
The shelf life in a closed tube is 2 years.
After first opening, the contents of the tube should be used for more than 6 weeks.
Reviews
There are no reviews yet.